Pointers to Cancer Prognosis

The last 30 years have seen little improvement in the age-adjusted mortality rates for most common types of cancer, and until we develop more effective and less damaging treatment modalities for these tumours, selection of each patient's ...

Pointers to Cancer Prognosis

The last 30 years have seen little improvement in the age-adjusted mortality rates for most common types of cancer, and until we develop more effective and less damaging treatment modalities for these tumours, selection of each patient's treatment must depend on prognostic pointers. These lead to a calculated trade off between our estimate of likely benefit to the patient, as against cost in terms of quality of life. But changes have occurred recently in our understanding of the traditional prognostic pointers used for selecting such individualised treatment. First, it is increasingly recognised that the stage at which a tumour presents is more related to the chromo logical age of the tumour (how far it has progressed before diagnosis) than to its biological characteristics. While advanced chronological age of the tumour may predict a greater likelihood of early death, only biological criteria can predict the tumour growth rate, the likelihood of prolonged survival, the likely course of the disease after the first recurrence or the likehood of response to systemic therapy. Second, there is increasing use of failure analysis in relating the clinical and biological characteristics of tumours to their response to standard treatments. In the past, the relationship was interpreted mainly in terms of survival rate, but the site and timing of first recurrence and the pattern and timing of subsequent spread provide a better assessment of the control possible from local or systemic therapy.

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Pointers to Cancer Prognosis
Language: en
Pages: 368
Authors: B.A. Stoll
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

The last 30 years have seen little improvement in the age-adjusted mortality rates for most common types of cancer, and until we develop more effective and less damaging treatment modalities for these tumours, selection of each patient's treatment must depend on prognostic pointers. These lead to a calculated trade off
Pointers to Cancer Prognosis
Language: en
Pages: 388
Authors: B a Stoll
Categories: Medical
Type: BOOK - Published: 1987-02-28 - Publisher:

Books about Pointers to Cancer Prognosis
Journal of the National Cancer Institute
Language: en
Pages:
Authors: B a Stoll
Categories: Medical
Type: BOOK - Published: 1988 - Publisher:

"Summaries of papers" contained in the journal accompany each issue, 19--
Women at High Risk to Breast Cancer
Language: en
Pages: 136
Authors: B.A. Stoll
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

A reprint of the 1989 edition of this book has been made necessary by continuing demand after rapid exhaustion of the first printing. In the two years since its appearance, there has been relatively little expansion of knowledge on this topic, and its massive accumulation of references still remains an
Journal of the National Cancer Institute
Language: en
Pages:
Authors: B.A. Stoll
Categories: Cancer
Type: BOOK - Published: 1990 - Publisher:

Books about Journal of the National Cancer Institute